scientificsupplyandequipment

Mastery Learning Ensures Correct Personal Protective Equipment Use in Simulated

Mastery Studying Ensures Right Private Protecting Gear Use in Simulated Scientific Encounters of COVID-19

Introduction: The proper use of private protecting tools (PPE) limits transmission of great communicable illnesses to healthcare staff, which is critically necessary within the period of coronavirus illness 2019 (COVID-19). Nonetheless, prior research illustrated that healthcare staff ceaselessly err throughout utility and elimination of PPE. The aim of this examine was to find out whether or not a simulation-based, mastery studying intervention with deliberate apply improves right use of PPE by physicians throughout a simulated medical encounter with a COVID-19 affected person.

 

Strategies: 

  • This was a pretest-posttest examine carried out within the emergency division at a big, tutorial tertiary care hospital between March 31-April 8, 2020. A complete of 117 topics participated, together with 56 college members and 61 resident physicians. Previous to the intervention, all individuals obtained institution-mandated schooling on PPE use by way of an internet video and supplemental supplies.

 

  • Members accomplished a pretest abilities evaluation utilizing a 21-item guidelines of steps to accurately don and doff PPE. Members have been anticipated to satisfy a minimal passing rating (MPS) of 100%, decided by an knowledgeable panel utilizing the Mastery Angoff and Affected person Security standard-setting strategies. Members that met the MPS on pretest have been exempt from the tutorial intervention.

 

  • Testing occurred earlier than and after an in-person demonstration of correct donning and doffing strategies and 20 minutes of deliberate apply. The first final result was a change in evaluation scores of right PPE use following our instructional intervention. Secondary outcomes included variations in efficiency scores between college members and resident physicians, and variations in efficiency throughout donning vs doffing sequences.

 

Outcomes: All individuals had a imply pretest rating of 73.1% (95% confidence interval [CI], 70.9-75.3%). School member and resident pretest scores have been comparable (75.1% vs 71.3%, p = 0.082). Imply pretest doffing scores have been decrease than donning scores throughout all individuals (65.8% vs 82.8%, p<0.001). Participant scores elevated 26.9% (95% CI of the distinction 24.7-29.1%, p<0.001) following our instructional intervention leading to all individuals assembly the MPS of 100%.

 

Conclusion: A mastery studying intervention with deliberate apply ensured the right use of PPE by doctor topics in a simulated medical encounter of a COVID-19 affected person. Additional examine of translational outcomes is required.

 

scientificsupplyandequipment
scientificsupplyandequipment

anti- IL-4 antibody

FNab04278 100µg
EUR 585
Description: Antibody raised against IL-4

anti- IL-4 antibody

FNab04279 100µg
EUR 585
Description: Antibody raised against IL-4

anti- IL-4 antibody

FNab09861 100µg
EUR 548.75
Description: Antibody raised against IL-4

anti- IL-4 antibody

LSMab09861 100 ug
EUR 386

Anti-IL-4 antibody

PAab04278 100 ug
EUR 412

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Recombinant Human IL-2 Protein

PROTP60568-4 50ug
EUR 317
Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Recombinant Human IL-17F Protein

PROTQ96PD4-4 25ug
EUR 317
Description: IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant human IL-17F is a disulfide-linked homodimer of 30.1 kDa, consisting of two 133 amino acid residue chains.

Recombinant Human IL-6 Protein

PROTP05231-4 20ug
EUR 317
Description: IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.

Recombinant Human IL-3 Protein

PROTP08700-4 10ug
EUR 317
Description: IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.

mAb mouse anti-human IL-4

CT253 0.5 mg
EUR 260

Anti-mouse IL-4 antibody

STJ15100035 250 µg
EUR 336
Description: This monoclonal antibody enables sensitive and specific detection of mouse IL-4 in immunoassays such as ELISA and ELISpot.

Anti-mouse IL-4 antibody

STJ15100036 500 µg
EUR 527
Description: This monoclonal antibody is recommended for neutralization of mouse IL-4 bioactivity.

Anti-mouse IL-4 antibody

STJ15100037 250 µg
EUR 367
Description: This monoclonal antibody enables sensitive and specific detection of mouse IL-4 in immunoassays such as ELISA and ELISpot.

Anti-IL-4 alpha antibody

STJ97665 200 µl
EUR 197
Description: Rabbit polyclonal to IL-4Ralpha.

Anti-IL-4 alpha antibody

STJ93702 200 µl
EUR 197
Description: Rabbit polyclonal to IL-4Ralpha.

Anti-IL-4 alpha antibody

STJ93703 200 µl
EUR 197
Description: Rabbit polyclonal to IL-4Ralpha.

Recombinant Human IL-12 p80 Protein

PROTP29460-4 10ug
EUR 317
Description: IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or can form a homodimer designated as IL-12 p80. Elevated levels of IL-12 p80 are correlated with macrophage recruitment and increased inflammation in asthma and respiratory viral infection models. Recombinant human IL-12 p80 is an 80.0 kDa disulfide linked homodimer consisting of two p40 chains of IL-12.

Recombinant Human IL-13 Variant Protein

PROTP35225-4 10ug
EUR 317
Description: IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. A variant of IL-13 shows enhanced functional activity compared with the wild type IL-13. PeproTech's genetic variant, termed human IL-13 analog, is a mature 114 amino acid protein with a substitution of Q for R at position 112.

Human Interleukin-4 (IL-4)

1-CSB-EP011659HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Interleukin-4(IL-4) expressed in E.coli

IL-4, Interleukin-4, human

RC212-15 5ug
EUR 104.38

Recombinant Human IL-16 (129 a.a.) Protein

PROTQ14005-4 10ug
EUR 317
Description: IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity. Recombinant human IL-16 is a 13.5 kDa protein consisting of 130 amino acid residues.

pAb rabbit anti-human IL-4 receptor

CT248 0.5 mg
EUR 184

IL-4

E21-050 10ug
EUR 343

IL-4

E21-D03 10ug
EUR 343

IL-4

E21-K15 10ug
EUR 343

IL-4

E13-015-1 10μg
EUR 161

IL-4

E13-015-2 50μg
EUR 505

IL-4

MO15071 500 ug
EUR 910

Recombinant Human IL-8 (72 a.a.) (CXCL8) Protein

PROTP10145-4 25ug
EUR 317
Description: IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant human IL-8 (monocyte-derived) is an 8.4 kDa protein containing 72 amino acid residues.

mAb mouse anti-rat IL-4

CT028 0.5 mg
EUR 260

mAb mouse anti-rat IL-4

CT029 0.5 mg
EUR 260

pAb rabbit anti-rat IL-4

CT058 0.5 mg
EUR 184

mAb mouse anti-monkey IL-4

CT103 0.5 mg
EUR 260

mAb rat anti-mouse IL-4

CT324 0.5 mg
EUR 260

mAb rat anti-mouse IL-4

CT337 0.5 mg
EUR 260

Swine IL-10 Recombinant Protein

R00021-4 5ug/vial
EUR 259
Description: IL-10 is an anti-inflammatory cytokine and a member of the IL-10 family of cytokines, which have indispensable functions in many infectious and inflammatory diseases. Swine IL-10 Recombinant Protein is purified interleukin-10 produced in yeast.

Mouse IL-13 Recombinant Protein

R00077-4 5ug/vial
EUR 259
Description: IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. Mouse IL-13 Recombinant Protein is purified interleukin-13 produced in yeast.

Feline IL-6 Recombinant Protein

R00102-4 5ug/vial
EUR 259
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Feline IL-6 Recombinant Protein is purified interleukin-6 produced in yeast.

Feline IL-2 Recombinant Protein

R00387-4 5ug/vial
EUR 259
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Feline IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.

Mouse IL-17A Recombinant Protein

R00421-4 5ug/vial
EUR 259
Description: IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Mouse IL-17A Recombinant Protein is purified interleukin-17A produced in yeast.

Dolphin IL-8 Recombinant Protein

R00423-4 5ug/vial
EUR 259
Description: Interleukin-8 (IL-8), also known as CXCL8, is an ELR-positive CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. Dolphin IL-8 Recombinant Protein is purified interleukin-8 produced in yeast.

Swine IL-21 Recombinant Protein

R00459-4 5ug/vial
EUR 259
Description: The cytokine interleukin-21 (IL-21) regulates the proliferation and differentiation of T and B lymphocytes, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. Swine IL-21 Recombinant Protein is purified interleukin-21 produced in yeast.

Equine IL-1ra Recombinant Protein

R00651-4 5ug/vial
EUR 259
Description: Interleukin-1 Receptor Antagonist Protein (IL-1F3, IL-1ra) belongs to the IL-1 family of cytokines, whose members play key roles in the development and regulation of inflammation. IL-1 receptor antagonist (IL-1ra; IL-1F3) reduces inflammation by blocking the binding of the agonist receptor ligands. Equine IL-1 Receptor Antagonist Recombinant Protein is purified interleukin-1 receptor antagonist protein (IL-1F3, IL-1ra) produced in yeast.

Human IL-4 Protein

abx060798-20ug 20 ug
EUR 467

Recombinant Human IL-4

P0052 100ug
EUR 522.36
Description: Recombinant Human protein for IL-4

rec IL-4 (human)

H-9630.0002 2.0µg
EUR 261

rec IL-4 (human)

H-9630.0010 10.0µg
EUR 950

Recombinant Human IL-4

SJB02-03 10µg/vial
EUR 285

Recombinant Human IL-4

SJB02-05 100µg/vial
EUR 720

Recombinant Human IL-4

SJB02-06 30µg/vial
EUR 430

IL-4, human recombinant

4137-10
EUR 278

IL-4, human recombinant

4137-1000
EUR 3704

IL-4, human recombinant

4137-50
EUR 697

Interleukin-4/IL-4

E21-K74 10ug
EUR 343

Human Interleukin-4 (IL-4) Antibody

32184-05111 150 ug
EUR 261

IL-7 Interleukin-7 Human Recombinant Protein, His Tag

PROTP13232-4 Regular: 10ug
EUR 317
Description: IL-7 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 152 amino acids fragment (26-177) and having a total molecular mass of 21.97 kDa with an amino-terminal hexahistidine tag. ;The IL-7 His-Tag protein is purified by proprietary chromatographic techniques.

Recombinant Human 4-1BB Receptor Protein

PROTQ07011-4 20ug
EUR 317
Description: 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant human soluble 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine rich TNFR-like extracellular domain of 4-1BB Receptor.

Recombinant Human PF-4 (CXCL4) Protein

PROTP02776-4 20ug
EUR 317
Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Human FibrOut 4, for brain, neural

4-21552 1 ml Ask for price

Human FibrOut 4, for brain, neural

4-21553 5 x 1 ml Ask for price

Feline IL-1 beta Recombinant Protein

R00101-4 5ug/vial
EUR 259
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Feline IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Feline IL-1 alpha Recombinant Protein

R01144-4 5ug/vial
EUR 259
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Feline IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

IL-4 antigen

E6IE600107 20ug
EUR 343

IL-4 antigen

E6L00107 20ug
EUR 382

rHu IL-4

AK8329-0005 5µg Ask for price

rHu IL-4

AK8329-0020 20µg Ask for price

rHu IL-4

AK8329-0100 100µg Ask for price

rHu IL-4

AK8329-1000 1mg Ask for price

IL-4 antibody

PAab09861 100 ug
EUR 386

IL-4 Antibody

5137-200
EUR 370

IL-4 Antibody

5137-30T
EUR 146

Anti-Phospho-IL-4 alpha (Y497) antibody

STJ90720 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-IL-4Ralpha (Y497).

Anti-IL-4 Antibody [11B11], Unconjugated-100ug

QAB81-100ug 100ug
EUR 149

Anti-IL-4 Antibody [11B11], Unconjugated-500ug

QAB81-500ug 500ug
EUR 233

Anti-IL-4 Antibody [11B11], APC-100ug

QAB81-APC-100ug 100ug
EUR 276

Anti-IL-4 Antibody [11B11], APC-25ug

QAB81-APC-25ug 25ug
EUR 131

Anti-IL-4 Antibody [11B11], PE-100ug

QAB81-PE-100ug 100ug
EUR 259

Anti-IL-4 Antibody [11B11], PE-25ug

QAB81-PE-25ug 25ug
EUR 141

IL-4, Interleukin-4, monkey

RC222-15 5ug
EUR 104.38

IL-4, Interleukin-4, rat

RC252-15 5ug
EUR 104.38

Interleukin 4 (IL-4) Antibody

abx234279-100ug 100 ug
EUR 551

Human Interleukin 4, IL-4 ELISA KIT

CSB-E04633h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 4, IL-4 in samples from serum, tissue homogenates, cell culture supernates, saliva. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Interleukin 4, IL-4 ELISA KIT

1-CSB-E04633h
  • EUR 500.00
  • EUR 3402.00
  • EUR 1820.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 4, IL-4 in samples from serum, tissue homogenates, cell culture supernates, saliva. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Interleukin 4(IL-4)ELISA Kit

GA-E0132HM-48T 48T
EUR 289

Human Interleukin 4(IL-4)ELISA Kit

GA-E0132HM-96T 96T
EUR 466

IL-4 Interleukin-4 Human Recombinant Protein

PROTP05112-1 Regular: 20ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a molecular mass of 15kDa. ;The IL-4 is purified by proprietary chromatographic techniques.

Human Interleukin 4,IL-4 ELISA KIT

201-12-0093 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin 4 (IL-4) CLIA Kit

abx195899-96tests 96 tests
EUR 825

Human Interleukin 4(IL-4)ELISA Kit

QY-E04267 96T
EUR 361

Human IL-4(Interleukin 4) ELISA Kit

EH0199 96T
EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human Interleukin 4,IL-4 ELISA KIT

CN-03206H1 96T
EUR 434

Human Interleukin 4,IL-4 ELISA KIT

CN-03206H2 48T
EUR 284

Human Interleukin-4 (IL-4) ELISA Kit

LF-EK60025 1×96T
EUR 790

Recombinant Human Interleukin-4 (rHu IL-4)

AK9839-0010 10ug
EUR 650

Recombinant Human Interleukin-4 (rHu IL-4)

AK9839-0030 30ug
EUR 1130

Recombinant Human IL-4 Protein

RP00995 5 μg
EUR 136

Recombinant Human IL-4 Protein

PROTP05112-5 15ug
EUR 317
Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 15.1 kDa globular protein containing 130 amino acid residues.

Human IL-4 Recombinant Protein

R00230-5 5ug/vial
EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Human IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

IL-4 (CHO-expressed), Human

HY-P7042 50ug
EUR 555

human IL-4, His tag

E410A04-100 100μg
EUR 960

Human IL-4 ELISA Kit

RK00003 96 Tests
EUR 521

Human IL-4 ELISA kit

CT203A 5-plate
EUR 462

Human IL-4 ELISPOT kit

CT232-PB2 2-plate
EUR 415

Human IL-4 ELISPOT kit

CT232-PB5 5-plate
EUR 568

Human IL-4 ELISPOT kit

CT232-PR2 2-plate
EUR 415

Human IL-4 ELISPOT kit

CT232-PR5 5-plate
EUR 556

Human IL-4 ELISPOT kit

CT232-T2 2-plate
EUR 360

Human IL-4 ELISPOT kit

CT232-T5 5-plate
EUR 579

IL-4 ELISA KIT|Human

EF000163 96 Tests
EUR 689

Human IL-4 ELISA kit

LF-EK50141 1×96T
EUR 648

IL-4 (Human) ELISA Kit

K4164-100
EUR 729

Recombinant Human Interleukin-4/IL-4 (Human Cells)

CX03-10ug 10ug
EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-4/IL-4 (Human Cells)

CX03-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-4/IL-4 (Human Cells)

CX03-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-4/IL-4 (Human Cells)

CX03-50ug 50ug
EUR 339
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Individual Reaction Mix 4

G065-4 200 reactions
EUR 167

Human CellExp? IL-4, Human Recombinant

6463-10
EUR 398

Human CellExp? IL-4, Human Recombinant

6463-50
EUR 1398

pLenti-CLDN1 shRNA-4 Plasmid

PVTBAV04867-4 2 ug
EUR 356

ELISA kit for Human IL-4 (Interleukin 4)

E-EL-H0101 1 plate of 96 wells
EUR 377
Description: A sandwich ELISA kit for quantitative measurement of Human IL-4 (Interleukin 4) in samples from Serum, Plasma, Cell supernatant

IL-4 Interleukin-4 Human Recombinant Protein, HEK

PROTP05112 Regular: 10ug
EUR 317
Description: IL-4 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 14-19kDa due to glycosylation.;The IL-4 is purified by proprietary chromatographic techniques.

IL-4 Interleukin-4 Human Recombinant Protein, CHO

PROTP05112-2 Regular: 10ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in CHO is a single, non-glycosylated polypeptide chain containing 129 amino acids and having a molecular mass of 14 kDa, the glycosilation of IL-4 migrates as 18 kDa on SDS-PAGE.;The IL-4 is purified by proprietary chromatographic techniques.

CLIA kit for Human IL-4 (Interleukin 4)

E-CL-H0100 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Human IL-4 (Interleukin 4) in samples from Serum, Plasma, Cell supernatant

Human Interleukin-4 (IL-4) Antibody (Biotin Conjugate)

32184-05121 150 ug
EUR 369

Human Interleukin 4 (IL-4) Detection Assay Kit

6803 1 kit
EUR 483.55
Description: Human Interleukin 4 (IL-4) Detection Assay Kit

Recombinant Human Interleukin-4/IL-4 (E. coli)

C050-10ug 10ug
EUR 168
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-4/IL-4 (E. coli)

C050-1mg 1mg
EUR 1836
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-4/IL-4 (E. coli)

C050-500ug 500ug
EUR 1298
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human Interleukin-4/IL-4 (E. coli)

C050-50ug 50ug
EUR 405
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

pAb rabbit anti-rat IL-4 Biotin-labeled

CT060 0.5 mg
EUR 347

Anti-IL-4 Antibody [11B11], Qfluor 630-100ug

QAB81-QF630-100ug 100ug
EUR 225

Anti-IL-4 Antibody [11B11], Qfluor 630-500ug

QAB81-QF630-500ug 500ug
EUR 310

Anti-IL-4 Antibody [MP4-25D2], APC-100Tests

QAB82-APC-100Tests 100Tests
EUR 251

Anti-IL-4 Antibody [MP4-25D2], APC-25Tests

QAB82-APC-25Tests 25Tests
EUR 141

Anti-IL-4 Antibody [MP4-25D2], PE-100Tests

QAB82-PE-100Tests 100Tests
EUR 276

Anti-IL-4 Antibody [MP4-25D2], PE-25Tests

QAB82-PE-25Tests 25Tests
EUR 141

IL-4, Interleukin-4, murine (mouse)

RC232-15 5ug
EUR 104.38

Recombinant Mouse Interleukin-4/IL-4

CK15-10ug 10ug
EUR 146
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Mouse Interleukin-4/IL-4

CK15-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Mouse Interleukin-4/IL-4

CK15-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Mouse Interleukin-4/IL-4

CK15-50ug 50ug
EUR 339
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 4 vials)

M1040-4
EUR 909

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 4 vials)

M1041-4
EUR 1137

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 4 vials)

M1042-4
EUR 909

ExoStd? Lyophilized Exosome Standard (100 µg, Human Serum, 4 vials)

M1043-4
EUR 1132

ExoStd? Lyophilized Exosome Standard (30 µg, Human Urine, 4 vials)

M1044-4
EUR 909

ExoStd? Lyophilized Exosome Standard (100 µg, Human Urine, 4 vials)

M1045-4
EUR 1137

ExoStd? Lyophilized Exosome Standard (30 µg, Human Saliva, 4 vials)

M1046-4
EUR 914

ExoStd? Lyophilized Exosome Standard (100 µg, Human Saliva, 4 vials)

M1047-4
EUR 1137

IL-4 Polyclonal Antibody

ES3875-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against IL-4 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

IL-4 Polyclonal Antibody

ES3875-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against IL-4 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

IL-4 Polyclonal Antibody

ES5877-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against IL-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

IL-4 Polyclonal Antibody

ES5877-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against IL-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

IL-4 Polyclonal Antibody

ES5878-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against IL-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

IL-4 Polyclonal Antibody

ES5878-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against IL-4 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

IL-4 GMP, CF

PR15114CF 50 ug
EUR 1615

 

Medical interns’ reflections on their coaching in use of private protecting tools

 

Background: The present COVID-19 pandemic has demonstrated that non-public protecting tools (PPE) is crucial, to forestall the acquisition and transmission of infectious illnesses, but its use is commonly sub-optimal within the medical setting.

 

Coaching and schooling are necessary to make sure and maintain the protected and efficient use of PPE by medical interns, however present strategies are sometimes insufficient in offering the related information and abilities. The aim of this examine was to discover medical graduates’ experiences of the usage of PPE and determine alternatives for enchancment in schooling and coaching programmes, to enhance occupational and affected person security.

 

Strategies: This examine was undertaken in 2018 in a big tertiary-care educating hospital in Sydney, Australia, to discover medical interns’ self-reported experiences of PPE use, firstly of their internship. Reflexive teams have been carried out instantly after theoretical and sensible PPE coaching, throughout hospital orientation. Transcripts of recorded discussions have been analysed, utilizing a thematic strategy that drew on the COM-B (functionality, alternative, motivation – behaviour) framework for behaviour.

 

Outcomes: 80% of 90 eligible graduates participated. Many interns had not beforehand obtained formal coaching within the particular abilities required for optimum PPE use and had developed probably unsafe habits. Their experiences as medical college students in medical areas contrasted sharply with beneficial apply taught at hospital orientation and impacted on their skill to domesticate right PPE use.

 

Conclusions: Undergraduate educating needs to be in line with finest apply PPE use, and embody sensible coaching that embeds right and protected practices.

Social Media Survey and Internet Posting Evaluation of the COVID-19 Response in China: Well being Employee Attitudes Towards Preparedness and Private Protecting Gear Shortages

 

Background: Understanding well being employee consciousness, attitudes, and self-confidence within the office can inform native and international responses towards rising infectious threats, just like the coronavirus illness 2019 (COVID-19) pandemic. Availability of accessible private protecting tools (PPE) is important to efficient care and prevention.
Strategies: We carried out a cross-sectional survey from February 24 to 28, 2020, to evaluate COVID-19 preparedness amongst well being staff. As well as, we assessed traits from search engine net crawling and text-mining knowledge trending over the Sina Weibo platform from January 1 to March 3, 2020. Information have been abstracted on Chinese language outbreak preparedness.
Outcomes: Within the survey, we engaged 6350 individuals, of whom 1065 agreed to take part, and after an eligibility logic test, 1052 participated (16.6%). We accessed 412 web posts as to PPE availability.
Well being staff who have been glad with present preparedness to deal with COVID-19 have been extra more likely to be feminine, to acquire information concerning the extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak from authorities organizations, and to contemplate their hospital ready for outbreak administration.
Well being staff with extra confidence of their skills to reply have been these with extra religion of their establishment’s response capacities. Components of readiness included having airborne an infection isolation rooms, customer management procedures, and coaching in precautions and PPE use. Each survey and net submit assessments steered that well being staff in want have been unable to reliably receive PPE.
Conclusions: Well being staff’ self-confidence relies on perceived institutional readiness. Failure to take care of obtainable PPE stock for rising infectious illnesses preparedness suggests a failure to be taught key classes from the 2003-2004 SARS outbreak in China.

Utilizing Giant-Scale Additive Manufacturing as a Bridge Manufacturing Course of in Response to Shortages in Private Protecting Gear in the course of the COVID-19 Outbreak

 

The worldwide coronavirus illness (COVID)-19 pandemic has led to a global scarcity of private protecting tools (PPE), with conventional provide chains unable to deal with the numerous demand resulting in essential shortfalls. Quite a few open and crowdsourcing initiatives have sought to deal with this shortfall by producing tools comparable to protecting face shields utilizing additive manufacturing strategies comparable to fused filament fabrication (FFF).
This paper experiences the method of designing and manufacturing protecting face shields utilizing large-scale additive manufacturing (LSAM) to supply the main thermoplastic parts of the face protect. LSAM presents vital benefits over different additive manufacturing applied sciences in bridge manufacturing eventualities as a real transition between prototypes and mass manufacturing strategies comparable to injection molding.
Within the context of manufacturing of COVID-19 face shields, the power to supply the optimized parts in beneath 5 min in comparison with what would sometimes take 1 – 2 h utilizing one other additive manufacturing applied sciences meant that vital manufacturing quantity might be achieved quickly with minimal staffing.

Anti-Dkk-1 antibody

STJ97257 200 µl
EUR 197
Description: Rabbit polyclonal to Dkk-1.

Anti-Dkk-1 antibody

STJ98000 100 µl
EUR 234
Description: Mouse monoclonal to Dkk-1.

Dkk-1 Polyclonal Antibody

41928-100ul 100ul
EUR 252

Dkk-1 Polyclonal Antibody

41928-50ul 50ul
EUR 187

DKK-1 Recombinant Protein

40-225-0002mg 0.002 mg
EUR 259.25
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

DKK-1 Recombinant Protein

40-225-001mg 0.01 mg
EUR 364.25
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

DKK 1 Recombinant Protein

96-236 0.1 mg
EUR 626.75
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression.

DKK 1 Recombinant Protein

96-237 0.025 mg
EUR 516.5
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression.

Dkk-1 Recombinant Protein

96-861 0.1 mg
EUR 542.75
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression.

Dkk-1 Recombinant Protein

96-990 0.05 mg
EUR 595.25
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression.

Human CellExp? DKK-1, Human Recombinant

7132-10
EUR 278

Human CellExp? DKK-1, Human Recombinant

7132-50
EUR 1132

Dkk-2

GT15222 100 ug
EUR 526

Human DKK-1 PicoKine ELISA Kit

EK0867 96 wells
EUR 425
Description: For quantitative detection of human DKK1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

ELISA kit for Human DKK-1

EK5390 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Recombinant Mouse Dkk-1 Protein

RP01062 5 μg
EUR 183

DKK-1 (CHO-expressed), Mouse

HY-P7154 50ug
EUR 762

Dkk-1 Polyclonal Conjugated Antibody

C41928 100ul
EUR 397

Human DKK-1 ELISA kit (4×96T)

LF-EK50798 4×96T
EUR 2201

Nori® Human DKK-1 ELISA Kit

GR106268 96-well
EUR 461

Dkk-3 antibody

22898-100ul 100ul
EUR 390

Recombinant Human Dkk-3 Protein

RP00355 10 μg
EUR 164

DKK-3 ELISA KIT|Human

EF000091 96 Tests
EUR 689

ELISA kit for Rat DKK-1

EK5668 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human DKK-1(Dickkopf-related protein 1) ELISA Kit

EH0113 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Dkk-1 ELISA Kit (Human) : 96 Wells (OKAG00221)

OKAG00221 96 Wells
EUR 596
Description: Description of target: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 63 pg/mL

Dkk-3 Polyclonal Antibody

ES5541-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Dkk-3 Polyclonal Antibody

ES5541-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Dkk-3 Polyclonal Antibody

ABP54542-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160

Dkk-3 Polyclonal Antibody

ABP54542-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160

Dkk-3 Polyclonal Antibody

ABP54542-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160

Anti-Dkk-3 antibody

STJ98001 100 µl
EUR 234
Description: Mouse monoclonal to Dkk-3.

Anti-Dkk-3 antibody

STJ92720 200 µl
EUR 197
Description: Rabbit polyclonal to Dkk-3.

DKK-2 Recombinant Protein

40-651 2 ug
EUR 259.25
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions.

DKK-3 Recombinant Protein

40-652 2 ug
EUR 259.25
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-L1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane co-receptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant Human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, Human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions.

DKK 3 Recombinant Protein

96-239 0.2 mg
EUR 684.5
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported.

Dkk-3 Recombinant Protein

96-991 0.05 mg
EUR 542.75
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported.

Recombinant Human Dkk-3/DKK3 Protein

RP00209 10 μg
EUR 155

Human DKK-4 PicoKine ELISA Kit

EK0868 96 wells
EUR 455
Description: For Quantitative Detection of human DKK-4 in cell culture supernates, serum and plasma(heparin, EDTA).

DKK-3 ELISA Kit (Human) (OKBB00603)

OKBB00603 96 Wells
EUR 505
Description: Description of target: Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Nori® Human DKK-1 ELISA Kit (2 plates)

GR106268-2 2 x 96-well
EUR 832

Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc]

VAng-1451Lsx-100g 100 µg
EUR 848
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1)

Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc]

VAng-1451Lsx-1mg 1 mg
EUR 4724
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1)

Recombinant Dkk-1 Protein (Thr 32-His 266) [His]

VAng-1453Lsx-100g 100 µg
EUR 1013
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1)

Recombinant Dkk-1 Protein (Thr 32-His 266) [His]

VAng-1453Lsx-1mg 1 mg
EUR 4999
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1)

Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep]

VAng-1454Lsx-1mg 1 mg
EUR 6374
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1)

Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep]

VAng-1454Lsx-250g 250 µg
EUR 2470
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1)

Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep]

VAng-1454Lsx-25g 25 µg
EUR 765
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1)

Recombinant Dkk-1 Protein (Thr 32-His 272) [His]

VAng-1455Lsx-500g 500 µg
EUR 4449
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908)

Recombinant Dkk-1 Protein (Thr 32-His 272) [His]

VAng-1455Lsx-50g 50 µg
EUR 1013
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908)

Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi]

VAng-1452Lsx-200g 200 µg
EUR 3844
Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1)

Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi]

VAng-1452Lsx-25g 25 µg
EUR 1013
Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1)

Human DKK-3(Dickkopf-related protein 3) ELISA Kit

EH0114 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml

Hemokinin 1 (human)

B5318-1 1 mg
EUR 340

Endothelin-1 (1-15), amide, human

A1111-1 1 mg
EUR 722
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis.

Haptoglobin, (Phenotype 1-1) Human Plasma

7536-1
EUR 321

Recombinant Dkk-3 Protein (Pro 23-Ile 349) [His]

VAng-1456Lsx-1mg 1 mg
EUR 5494
Description: Mouse Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_056629.1)

Recombinant Dkk-3 Protein (Pro 23-Ile 349) [His]

VAng-1456Lsx-50g 50 µg
EUR 848
Description: Mouse Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_056629.1)

Recombinant Dkk-3 Protein (Pro 23-Ile 350) [His]

VAng-1457Lsx-200g 200 µg
EUR 1123
Description: Human Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001018067.1)

Recombinant Dkk-3 Protein (Pro 23-Ile 350) [His]

VAng-1457Lsx-20g 20 µg
EUR 380
Description: Human Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001018067.1)

IGF-1, human recombinant

P1016-.1 100 µg
EUR 763
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

BNP (1-32), human

A1105-1 1 mg
EUR 177
Description: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).

Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein

P1054-1 1 mg
EUR 3947
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation

Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His)

CC49-10ug 10ug
EUR 156
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.

Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His)

CC49-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.

Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His)

CC49-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.

Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His)

CC49-50ug 50ug
EUR 369
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2.

IL1RL1 Human, Interleukin-1 Receptor Like-1 Human Recombinant Protein, Sf9

PROTQ01638-1 Regular: 10ug
EUR 317
Description: IL 1RL1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-328 a.a.) and fused to an 8 aa His Tag at C-terminus containing a total of 318 amino acids and having a molecular mass of 36.0kDa.;IL 1RL1 shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein

PROTP03956-1 Regular: 20ug
EUR 317
Description: MMP 1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus.

PSG1 Human, Pregnancy Specific Beta-1-Glycoprotein 1 Human Recombinant Protein, Sf9

PROTP11464-1 Regular: 10ug
EUR 317
Description: PSG1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 394 amino acids (35-419a.a.) and having a molecular mass of 44.6kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). PSG1 is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

Recombinant Human ANG-1 Protein

PROTQ15389-1 20ug
EUR 317
Description: Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a tyrosine-kinase receptor expressed primarily on vascular endothelial cells and early hematopoietic cells. Ang-1/ Tie-2 signaling promotes angiogenesis during the development, remodeling, and repair of the vascular system. Transgenic mice lacking expression of either Ang-1 or Tie-2 fail to develop a fully functional cardiovascular system and die before birth. Postnatally, the angiogenic activity of Ang-1/Tie-2 is required during normal tissue repair and remodeling of the female endometrium in the menstrual cycle. Ang-1/Tie-2 signaling appears to be regulated by Angiopoietin-2 (Ang-2), a natural antagonist for Tie-2 that exerts its effects through an internal autocrine loop mechanism. In addition to suppressing endothelial cell activation by inhibiting the expression of adhesion and inflammatory molecules, Ang-1 enhances endothelial cell survival and capillary morphogenesis, and lessens capillary permeability. As such, Ang-1 has a potential to become an effective therapeutic agent for treating various endothelium disorders, including several severe human pulmonary diseases. The efficacy of cell-based Ang-1 gene therapy for acute lung injury (ALI) has recently been studied in a rat model of ALI (1). The results of this study show that such therapy can markedly improve lung condition and suggest that Ang-1 therapy may represent a potential new strategy for the treatment and/or prevention of acute respiratory distress injury (ARDI), a significant cause of morbidity and mortality in critically ill patients. Recombinant human ANG-1, derived from HeLa cells, is a C-terminal histidine tagged glycoprotein which migrates with an apparent molecular mass of 60.0 – 70.0 kDa by SDS-PAGE under reducing conditions. Sequencing analysis shows N-terminal sequences starting with Ser-20 and with Asp-70 of the 498 amino acid precursor protein.

ORM1 Orosomucoid 1 Human protein

PROTP02763-1 Regular: 10ug
EUR 317
Description: The Human Orosomucoid 1 produced from Human pooled serum has a molecular mass of 21.56kDa (calculated without glycosylation) containing 183 amino acid residues.

Recombinant Human Galectin-1 Protein

PROTP09382-1 50ug
EUR 317
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Recombinant Human PECAM-1 Protein

PROTP16284-1 50ug
EUR 317
Description: PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein containing a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions

Recombinant Human Gremlin-1 Protein

PROTO60565-1 50ug
EUR 317
Description: Gremlin-1 (isoform-1) belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Gremlin is highly expressed in the small intestine, fetal brain, and colon and lower expression in brain, prostate, pancreas and skeletal muscle.  Gremlin-1 regulates multiple functions in early development by specifically binding to and inhibiting the function of BMP-2, -4, and -7.  It also plays a role in carcinogenesis and kidney branching morphogenesis. Recombinant Gremlin-1 is a 18.3  kDa protein containing 160 amino acid residues.

ApoA-1, human recombinant protein

P1052-.1 100 µg
EUR 313
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion.

ApoA-1, human recombinant protein

P1052-1 1 mg
EUR 1553
Description: Apolipoprotein A-1 (ApoA-1) is a glycoprotein produced in the liver and intestine that is the major protein component of high density lipoprotein (HDL) particles. ApoA-1 is involved in the reverse transport of cholesterol from peripheral tissues to the liver for recycling and excretion.

WNT-1, human recombinant protein

P1068-1 1 mg
EUR 6940
Description: The WNT gene family compose of structurally related genes that encode secreted signaling proteins. These proteins have been involved in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.

Amyloid ?-Peptide (1-42) (human)

B6057-.1 100 ug
EUR 276

Parathyroid hormone (1-34) (human)

A1129-1 1 mg
EUR 166
Description: Parathyroid hormone (1-34) (human), (C181H291N55O51S2), a peptide with the sequence H2N-SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 4117.72.

(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein

PROTO75771-1 Regular: 10ug
EUR 317
Description: RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

NXPH1 Human, Neurexophilin 1 Human Recombinant Protein, Sf9

PROTP58417-1 Regular: 10ug
EUR 317
Description: NXPH1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 259 amino acids (22-271) and having a molecular mass of 29.7kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa).;NXPH1 is fused to 9 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.

GAD1 iso1 Glutamate Decarboxylase 1 Isoform-1 Human Recombinant Protein

PROTQ99259-1 Regular: 20ug
EUR 317
Description: GAD1 iso1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 617 amino acids (1-594 a.a) and having a molecular mass of 69.3kDa. GAD1 iso1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

TGF-b-1 Transforming Growth Factor-beta 1 Human protein

PROTP01137-1 Regular: 2.5ug
EUR 1157
Description: Human Transforming Growth Factor-beta 1 purified from Human Platelets having a molecular mass of 25kDa.;The TGF-b 1 is purified by proprietary chromatographic techniques.

MCP-1 Monocyte Chemotactic Protein-1 Human Recombinant Protein (CCL2)

PROTP13500-1 Regular: 20ug
EUR 317
Description: Monocyte Chemotactic Protein-1 Human Recombinant also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 76 amino acids and having a molecular mass of 8.6kDa. ;The MCP-1 is purified by proprietary chromatographic techniques.

Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EI2200-1 96 Well Plate
EUR 477

Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit

EI2301-1 96 Well Plate
EUR 477

Human KRAB-associated Protein 1 (KAP-1) AssayMax ELISA Kit

EK2802-1 96 Well Plate
EUR 477

Human Plasminogen Activator Inhibitor-1 (PAI-1) AssayMax ELISA Kit

EP1100-1 96 Well Plate
EUR 417

Recombinant Human Heregulin Beta -1 Protein

PROTQ02297-1 50ug
EUR 317
Description: Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity, which leads to tyrosine phosphorylation. Although HRG1-β1 biological effects is still unclear, it has been found to promote motility and invasiveness of breast cancer cells which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF). Recombinant human Heregulin-β1 (HRG1-β1) is a 7.5 kDa polypeptide consisting of only the EGF domain of Heregulin-β1 (65 amino acid residues).

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